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CDR111 is a trispecific M-gager, an antibody-based T-cell engager designed to selectively target and deplete B cells, with the goal of achieving immune system reset.
November 4, 2025
By: Charlie Sternberg
Associate Editor
Boehringer Ingelheim and CDR-Life Inc. have announced a new global licensing agreement to develop CDR-Life’s antibody-based molecule CDR111 for autoimmune diseases. CDR111 is a trispecific M-gager, an antibody-based T-cell engager designed to selectively target and deplete B cells, with the goal of achieving immune system reset. Dysregulated B cells play a central role in driving many autoimmune and inflammatory conditions such as lupus, multiple sclerosis and certain forms of arthritis. Ther...
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